Abstract

Review Article

Cannabinoids as a yield modifier in physical activit: A systematic review characters

Leonardo Tibiriçá Corrêa, Juliana Weckx Peña Muñoz, Beatriz do Prado Pacca Faria, Jeferson Santana, Leandro Yanase, EstherLopes Ricci, Lorena de Paula Pantaleon, Leonardo Ribeiro de Paula, Guilherme Mendes Ribeiro, Vinicius Barroso Hirota and André Rinaldi Fukushima*

Published: 28 July, 2021 | Volume 6 - Issue 3 | Pages: 018-021

Marijuana is considered illicit in much of the world, and is classified as a drug for recreational use, in recent decades the medicinal use of Cannabis sativa L. has grown and diversified, being considered the only therapeutic alternative in the control of serious and incurable diseases such as syndrome of Dravet. The world panorama has shown a more liberal position, since in several countries such as the United States of America, Holland, Australia, Italy, and more recently in Canada, the use of medications, or even the recreational use of this plant, have been regulated. In this context, the investigation of the modifying effects on physical activity of empirically used cannabinoids is fundamental nowadays, mainly due to the regulatory recognition of Cannabis sativa L. as a medicinal plant in a large part of the world. Therefore, the objective of this review was to verify the evidence related to the effect of cannabis on physical performance and to identify and highlight the challenges in the interpretation of information regarding the performance of practitioners of physical activity, as well as athletes, presenting new trends in this area of research to be addressed. To carry out the systematic review, a bibliographic survey of case reports was obtained through Pubmed, Science Direct and Google Academic databases. The following keywords were used to perform the research: cannabis, performance, pain, competition. The following filters were used as inclusion criteria a languages used english; species: humans; types of articles: original articles and reviews and period of publication of articles: 1981 to 2021.

Read Full Article HTML DOI: 10.29328/journal.jsmt.1001053 Cite this Article Read Full Article PDF

Keywords:

Marijuana; Physical activity; Competition; Doping

References

  1. Kennedy MC. Cannabis: exercise performance and sport. A systematic review. J Sci Med Sport. 2017; 20: 825–829. PubMed: https://pubmed.ncbi.nlm.nih.gov/28392338/
  2. Fraguas-Sanchez A, Torres-Suarez A. Medical use of cannabinoids. Drugs. 2018; 78: 1665-1703. PubMed: https://pubmed.ncbi.nlm.nih.gov/30374797/
  3. Aronow WS, Cassidy J. Effect of marijuana and placebo-marijuana smoking onangina pectoris. N Engl J Med. 1974; 291: 65–67. PubMed: https://pubmed.ncbi.nlm.nih.gov/4599385/
  4. World Anti-Doping Agency. International Standard for Laboratories. 2009. http://www.wada-ama.org/en/Science-Medicine/Anti-Doping- Laboratories/International-Standard-for-Laboratories/
  5. Devinsky O, Cross JH, Laux L. Trial of cannabidiol for drug-resistant seizures in the Dravet syndrome. N Engl J Med. 2017; 376: 2011–2020.
  6. Saugy M, Avois L, Saudan C, Robinson N, Giroud C, et al. Cannabis and sport. Br J Sports Med. 2006; 40: i13-i15. PubMed: https://pubmed.ncbi.nlm.nih.gov/16799094/
  7. Huestis MA, Mazzoni I, Rabin O. Cannabis in Sport Anti-Doping Perspective. Sports Med. 2011; 41: 949-966. PubMed: https://pubmed.ncbi.nlm.nih.gov/21985215/
  8. Huestis MA, Smith ML. Human cannabinoid pharmacokinetics and interpretation of cannabinoid concentrations in biological fluids and tissues. In: ElSohly MA, editor. Marijuana and the cannabinoids. Totowa (NJ): Humana Press. 2006: 205-236.
  9. World Health Organization. WHO guidelines on physical activity and sedentary behaviour. World Health Organization. 2020; PubMed: https://apps.who.int/iris/handle/10665/336656
  10. Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep. 1985; 100: 126-131. PubMed: https://pubmed.ncbi.nlm.nih.gov/3920711/
  11. Hu S, Mackie K. Distribution of the endocannabinoid system in the central nervous system. In: Pertwee, R. (ed.) Endocannabinoids. Handbook Experimen Pharmacol. 2015; 231: 59-93. PubMed: https://pubmed.ncbi.nlm.nih.gov/26408158/
  12. Woodhams SG, SagarDR, Burston JJ, Chapman C. The role of the endocannabinoid system in pain. Handb Exp Pharmacol. 2015; 227: 119–143. PubMed: https://pubmed.ncbi.nlm.nih.gov/25846617/
  13. Ware MA. Jensen D, Barrette A, Vernec A, Derman W. Cannabis and the Health and Performance of the Elite Athlete. Clin J Sport Med. 2018; 28: 480-484. PubMed: https://pubmed.ncbi.nlm.nih.gov/30153174/
  14. Thaskin DP, Shapiro BJ, Enoch Lee Y, Harper CE. Effects of smoked marijuana in exper-imentally induced asthma. Am Rev Respir Dis. 1975;; 112: 377–386. PubMed: https://pubmed.ncbi.nlm.nih.gov/1099949/
  15. Renaud AM, Cormier Y. Acute effects of marihuana smoking on maximal exercise performance. Med Sci Sports Exerc. 1986; 18: 685–689. PubMed: https://pubmed.ncbi.nlm.nih.gov/3097453/
  16. Bolla KI, Brown K, Eldreth D, Tate K, Cadet JL. Dose-related neurocognitive effects of marijuana use. Neurology. 2002; 59: 1337-1343. PubMed: https://pubmed.ncbi.nlm.nih.gov/12427880/
  17. Pertwee RG. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br J Pharmacol. 2009; 156: 397-411. PubMed: https://pubmed.ncbi.nlm.nih.gov/19226257/
  18. Ho W, Kelly M. Chapter ten: Cannabinoids in the Cardiovascular System. In: Kendall D, Alexander S (ed.). Cannabinoid Pharmacol. 2017; 80: 329-336.
  19. Tricker R, Connolly D. Drugs and the college athlete: an analysis of the attitudes of student athletes at risk. J Drug Educ. 1997; 27: 105–119. PubMed: https://pubmed.ncbi.nlm.nih.gov/9270209/
  20. Van Eenoo P, Delbeke FT. The prevalence of doping in Flanders in comparison to the prevalence of doping in international sports. Int J Sports Med. 2003; 24: 565–570. PubMed: https://pubmed.ncbi.nlm.nih.gov/14598191/
  21. Peretti-Watel P, Lorente FO. Cannabis use, sport practice and other leisure activities at the end of adolescence. Drug Alcohol Depend. 2004; 73: 251–257. PubMed: https://pubmed.ncbi.nlm.nih.gov/15036547/
  22. Brisola-Santos MB, Gallinaro JG, Gil F, Sampaio B Jr, Marin MCD, et al. Prevalence and correlates of cannabis use among athletes-a systematic review. Am J Addict. 2016; 25: 518–528. PubMed: https://pubmed.ncbi.nlm.nih.gov/27629700/
  23. Muñoz JWP, Machado TF, Luz J, Bello SG, Ricc EL, et al. Bone Graft as an Adjunctive Treatment for Delayed Union and Non-Union of Fractures in Dogs: Systematic Review. Global J Vet Care Res. 2020; 1: 1-7.
  24. Glass M, Dragunow M, Faull RL. Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain. Neuroscience. 1997; 77: 299-318. PubMed: https://pubmed.ncbi.nlm.nih.gov/9472392/
  25. Steadward RD, Singh M. The effects of smoking marihuana on physical performance. Med Sci Sports. 1975; 7: 309–311. PubMed: https://pubmed.ncbi.nlm.nih.gov/1235156/
  26. National Drug Strategy. Cannabis in Australia: use, supply and responses. Monograph Series no. 57. Canberra (ACT): Australian Government, Department of Health and Ageing, 2006.
  27. European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). A cannabis reader: global issues and local experiences. Monograph, series 8, Volume 2. Lisbon: EMCDDA, 2008.
  28. Moreira FA, Lutz B. The endocannabinoid system: emotion, learning and addiction. Addict Biol. 2008; 13: 196-212. PubMed: https://pubmed.ncbi.nlm.nih.gov/18422832/
  29. National Drug Strategy. Cannabis and mental health: put into context. Monograph Series no. 68. Canberra (ACT): Australian Government, Department of Health and Ageing, 2008.
  30. Spechlera PA, Orr CA, Chaarani B, Kan KJ, Mackey S, et al. Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat. Dev Cogn Neurosci. 2015; 16: 63-70. PubMed: https://pubmed.ncbi.nlm.nih.gov/26347227/
  31. Cordell GA. Sustainable drugs and global health care. Quím Nova. 2009; 32.

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